Ouabain inhibits p38 activation in thymocytes.

  title={Ouabain inhibits p38 activation in thymocytes.},
  author={Sandra Rodrigues-Mascarenhas and Flavia Fonseca Bloise and Jorge Moscat and Vivian M. Rumjanek},
  journal={Cell biology international},
  volume={32 10},
The MAPK p38 is phosphorylated by multiple stimuli and regulates a number of transcription factors. It is reported that activation of p38 leading to the regulation of NFAT may result from an alternative MKK-independent mechanism. This alternative pathway involves the protein Dlgh1 as an essential scaffold that assembles a module for the activation of p38… CONTINUE READING