Ouabain as a mammalian hormone.

@article{Schoner2003OuabainAA,
  title={Ouabain as a mammalian hormone.},
  author={W. Schoner and Natali B Bauer and Jochen M{\"u}ller-Ehmsen and U. Kr{\"a}mer and Njde Hambarchian and Robert H. G. Schwinger and Hans M{\"o}ller and Holger Kost and Christine Weitkamp and Thomas Schweitzer and Ulrike Kirch and Horst Neu and E G Gr{\"u}nbaum},
  journal={Annals of the New York Academy of Sciences},
  year={2003},
  volume={986},
  pages={678-84}
}
Endogenous ouabain changes rapidly in humans and dogs upon physical exercise and is under the control of epinephrine and angiotensin II. Hence, the steroid acts as a rapidly acting hormone. A search for a specific binding globulin for cardiac glycosides in bovine plasma resulted in the identification of the d allotype of the micro chain of IgM whose hydrophobic surfaces interact with cardiotonic steroids and cholesterol. Such IgM complexes might be involved in the hepatic elimination of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Epithelial Na+,K+-ATPase — A Sticky Pump

Teresa del Carmen López Murillo, Claudia Andrea Vilchis Nestor, María Luisa Roldán Gutierrez, Liora Shoshani
2017
View 2 Excerpts

Ouabain increases gap junctional communication in epithelial cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2014

Similar Papers

Loading similar papers…