Otto Warburg's contributions to current concepts of cancer metabolism

@article{Koppenol2011OttoWC,
  title={Otto Warburg's contributions to current concepts of cancer metabolism},
  author={Willem H Koppenol and Patricia L. Bounds and Chi V. Dang},
  journal={Nature Reviews Cancer},
  year={2011},
  volume={11},
  pages={618-618}
}
| Otto Warburg pioneered quantitative investigations of cancer cell metabolism, as well as photosynthesis and respiration. Warburg and co-workers showed in the 1920s that, under aerobic conditions, tumour tissues metabolize approximately tenfold more glucose to lactate in a given time than normal tissues, a phenomenon known as the Warburg effect. However, this increase in aerobic glycolysis in cancer cells is often erroneously thought to occur instead of mitochondrial respiration and has been… CONTINUE READING
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