Ototoxicity of topical ciprofloxacin/dexamethasone otic suspension in a chinchilla animal model.


OBJECTIVE To determine the ototoxic potential of ciprofloxacin/dexamethasone eardrops. METHODS Ventilation tubes were inserted in the ears of 15 chinchillas. One ear was randomized to receive four drops of ciprofloxacin/dexamethasone. A control solution (0.45% NaCl) was applied in the contralateral ear. The eardrops were delivered twice daily for 7… (More)
DOI: 10.1016/j.otohns.2008.08.005


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