Ototoxicity of salicylate, nonsteroidal antiinflammatory drugs, and quinine.


Salicylates and most NSAIDS in high doses cause mild to moderate temporary hearing loss, either flat or greater in the high frequencies. Hearing loss is accompanied by tinnitus and suprathreshold changes. Salicylates may or may not exacerbate hearing loss and cochlear damage induced by noise. The mechanism of salicylate ototoxicity seems to be… (More)


  • Blog articles referencing this paper

  • Presentations referencing similar topics