Otological manifestations of acute leukaemia: report of two cases and review of literature.

@article{Andres2001OtologicalMO,
  title={Otological manifestations of acute leukaemia: report of two cases and review of literature.},
  author={Emmanuel Andres and J E Kurtz and F r{\'e}d{\'e}ric Maloisel and Patrick Dufour},
  journal={Clinical and laboratory haematology},
  year={2001},
  volume={23 1},
  pages={57-60}
}
Otological manifestations exceptionally reveal acute leukaemia, whereas leukaemic infiltration of any tissue is frequent at postmortem examination. We present two cases of acute myeloblastic leukaemia revealed by a loss of hearing due to a middle-ear leukaemic infiltration. The characteristics of such a clinical and radiological finding are emphasized. It is suggested that middle and inner ear can be a 'sanctuary' localization, which might sometimes require radiation therapy to achieve durable… CONTINUE READING