Other Disorders Monoclonal Antibody for the Therapy of Solid Tumors and Humanization of an Anti-Vascular Endothelial Growth Factor

Abstract

Vascular endothelial growth factor (VE(ìF) is a major mediator of angiogenesis associated with tumors and other pathological conditions, including proliferative diahetic retinopathy and age-related macular degeneration. The murine anti-human \ I (.1 monoclonal antibody imiiM \l> \ I.di i A.4.6.1 has heen shown to potently suppress angiogenesis and growth… (More)

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