Oswald Avery, DNA, and the transformation of biology

@article{Cobb2014OswaldAD,
  title={Oswald Avery, DNA, and the transformation of biology},
  author={Matthew Cobb},
  journal={Current Biology},
  year={2014},
  volume={24},
  pages={R55-R60}
}
  • M. Cobb
  • Published 20 January 2014
  • History
  • Current Biology
View on Elsevier
doi.org
16 Citations
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16 Citations

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References

SHOWING 1-10 OF 58 REFERENCES
The transformation of genetics by DNA: an anniversary celebration of Avery, MacLeod and McCarty (1944).
In this article, Lederberg marked the fiftieth anniversary of the 1944 paper by Avery, MacLeod, and McCarty and the opening of the field of genetics.
Early responses to Avery et al.'s paper on DNA as hereditary material
TLDR
The responses to Avery9s et al.9s paper show how different research interests in the areas between microbiology, genetics, and biochemistry interacted with the prejudices, dogmas, individual farsightedness or short-sightedness, and scientific authority during a pivotal period of early molecular biology.
Transformation of Cells and Viruses
TLDR
Both the first and the second concerning a novel system of relations between the nucleus and cytoplasmic substances in heredity are of considerable potential significance for the study of differentiation and growth.
The Professor, the Institute, and DNA
RENA J. DUBOS, The Professor, the Institute, and DNA, New York, Rockefeller University Press, 1976, 8vo, pp. vii, 238, illus., $14.50. Oswald Theodore Avery (1877-1955), nicknamed "The Professor",…
The Transforming Principle : Discovering that genes are made ofDNA
TLDR
This was the dawn of molecular genetics, the first clear demonstration that genetic specificity was inscribed in the chemical structure of DNA.
Functional differentiation within particles of bacteriophage T2.
  • A. D. Hershey
  • Biology
    Cold Spring Harbor symposia on quantitative biology
  • 1953
TLDR
Some of the reasons for the current interest in the DNA of T2 are reviewed, and unfortunately I shall not be able to say anything of consequence about its function.
The chemical characterization of the gene: vicissitudes of evidential assessment.
  • J. Stegenga
  • Psychology
    History and philosophy of the life sciences
  • 2011
TLDR
It is argued that the changing context in which the evidence presented by Avery's group was interpreted partly explains the vicissitudes of the assessments of the evidence.
The Transforming Principle: Discovering that Genes Are Made of DNA
"The most interesting and portentous biological experiment of the 20th century authoritatively described by one of the three principal executants." Sir Peter Medawar "The education of the…
Prematurity and uniqueness in scientific discovery.
William Astbury and the biological significance of nucleic acids, 1938-1951.
  • Kersten Hall
  • Physics
    Studies in history and philosophy of biological and biomedical sciences
  • 2011
...
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