Ostreolysin, a pore-forming protein from the oyster mushroom, interacts specifically with membrane cholesterol-rich lipid domains.

@article{Sepi2004OstreolysinAP,
  title={Ostreolysin, a pore-forming protein from the oyster mushroom, interacts specifically with membrane cholesterol-rich lipid domains.},
  author={Kristina Sep{\vc}i{\'c} and Sabina Berne and Katja Rebolj and Ur{\vs}ka Batista and Ana Plemenita{\vs} and Marjeta Sentjurc and Peter Ma{\vc}ek},
  journal={FEBS letters},
  year={2004},
  volume={575 1-3},
  pages={81-5}
}
Ostreolysin, a 15 kDa pore-forming protein from the edible oyster mushroom (Pleurotus ostreatus), is lytic to membranes containing both cholesterol and sphingomyelin. Its cytotoxicity to Chinese hamster ovary cells correlates with their cholesterol contents and with the occurrence of ostreolysin in the cells detergent resistant membranes. Moreover, ostreolysin binds to supported monolayers and efficiently permeabilizes sonicated lipid vesicles, only if cholesterol is combined with either… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…