Osterix functions downstream of anti-Müllerian hormone signaling to regulate Müllerian duct regression.

  title={Osterix functions downstream of anti-M{\"u}llerian hormone signaling to regulate M{\"u}llerian duct regression.},
  author={Rachel D Mullen and Ying N. Wang and Bin Liu and Emma L Moore and Richard R. Behringer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={115 33},
In mammals, the developing reproductive tract primordium of male and female fetuses consists of the Wolffian duct and the Müllerian duct (MD), two epithelial tube pairs surrounded by mesenchyme. During male development, mesenchyme-epithelia interactions mediate MD regression to prevent its development into a uterus, oviduct, and upper vagina. It is well established that transforming growth factor-β family member anti-Müllerian hormone (AMH) secreted from the fetal testis and its type 1 and 2… CONTINUE READING
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