Osteosarcoma with epithelioid features. An immunohistochemical study.

  title={Osteosarcoma with epithelioid features. An immunohistochemical study.},
  author={Tomonobu Hasegawa and Taihoh Shibata and Takanori Hirose and Kunihiko Seki and Kazuoki Hizawa},
  journal={Archives of pathology & laboratory medicine},
  volume={117 3},
We report a case of osteosarcoma with coexpression of epithelial and mesenchymal markers immunohistochemically of the second lumbar vertebra in a 49-year-old man. Histologically, the tumor largely showed typical patterns of osteosarcoma with lacelike osteoid deposition and chondroblastic and fibroblastic areas. Immunoreactivity for osteocalcin (human bone gamma-carboxyglutamic acid-containing protein) was demonstrated in most of these tumor cells. Both primary and recurrent tumors contained… CONTINUE READING

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