Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy.

@article{Ketola2004OsteosarcomaAC,
  title={Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy.},
  author={Anna Ketola and Ann-Marie M{\"a}{\"a}tt{\"a} and Tiina Pasanen and Kirsi Tulim{\"a}ki and Jarmo Wahlfors},
  journal={International journal of molecular medicine},
  year={2004},
  volume={13 5},
  pages={705-10}
}
Osteosarcoma and chondrosarcoma, the most prevalent primary malignant tumors of the bone, have been demonstrated to be potential target diseases for herpes simplex virus type 1 thymidine kinase (HSV-TK)/ganciclovir (GCV) suicide gene therapy. However, the utility of this gene therapy form for bone tumor cells has not been studied systematically. In this… CONTINUE READING