Osteoprotegerin is associated with cardiovascular risk in hypertension and/or diabetes.

  title={Osteoprotegerin is associated with cardiovascular risk in hypertension and/or diabetes.},
  author={Ana M. Bl{\'a}zquez-Medela and Luis Garc{\'i}a-Ortiz and Manuel {\'A}ngel G{\'o}mez-Marcos and Jose Ignacio Recio-Rodriguez and Angel S{\'a}nchez-Rodr{\'i}guez and Jos{\'e} Miguel L{\'o}pez-Novoa and Carlos Mart{\'i}nez-Salgado},
  journal={European journal of clinical investigation},
  volume={42 5},
BACKGROUND Osteoprotegerin (OPG), a secreted member of the tumour necrosis factor receptor superfamily of cytokines, has been associated with endothelial dysfunction. We studied in type 2 diabetic and/or hypertensive patients the relationship between serum OPG and vascular alterations associated with these pathologies. MATERIALS AND METHODS We analysed 191 consecutive patients (52 with type 2 diabetes and 139 hypertensive nondiabetic patients) and 54 healthy controls. We assessed the… CONTINUE READING
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