Osteoporosis-bone remodeling and animal models.

  title={Osteoporosis-bone remodeling and animal models.},
  author={Ermanno Bonucci and Paola Ballanti},
  journal={Toxicologic pathology},
  volume={42 6},
Osteoporosis is a very common skeletal disorder characterized by reduced bone mass and altered trabecular microarchitecture that leads to bone fragility and fractures. Such disease is due to alterations of the remodeling process that occurs in the basic multicellular units that are transitory cellular complexes including an osteoclastic phase (osteoclast activation and resorption of microscopic portions of bone), a reversion phase (osteoclast replacement by so-called postosteoclastic cells… CONTINUE READING


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