Osteopontin and related SIBLING glycoprotein genes are expressed by Sertoli cells during mouse testis development.

@article{Wilson2005OsteopontinAR,
  title={Osteopontin and related SIBLING glycoprotein genes are expressed by Sertoli cells during mouse testis development.},
  author={Megan J. Wilson and Lucy Liaw and Peter Koopman},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2005},
  volume={233 4},
  pages={1488-95}
}
Matrix proteins play important roles in tissue morphogenesis. We have studied the expression of genes encoding the related SIBLING glycoproteins osteopontin (OPN), bone sialoprotein (BSP), and dentin matrix protein (DMP) during the development of male and female gonads during mouse embryogenesis. Opn mRNA was expressed specifically by Sertoli cells of the developing testis cords, in the mesonephric tubules of both sexes, and, transiently, in the Müllerian ducts of both sexes, as determined by… CONTINUE READING