Osteopontin and its spatiotemporal relationship with glial cells in the striatum of rats treated with mitochondrial toxin 3-nitropropionic acid: possible involvement in phagocytosis

@inproceedings{Riew2019OsteopontinAI,
  title={Osteopontin and its spatiotemporal relationship with glial cells in the striatum of rats treated with mitochondrial toxin 3-nitropropionic acid: possible involvement in phagocytosis},
  author={Tae-Ryong Riew and Soojin Kim and Xuyan Jin and Hong Lim Kim and Jeong-Hwa Lee and Mun-Yong Lee},
  booktitle={Journal of Neuroinflammation},
  year={2019}
}
BackgroundOsteopontin (OPN, SPP1) is upregulated in response to acute brain injury, and based on its immunoreactivity, two distinct forms have been identified: intracellular OPN within brain macrophages and small granular OPN, identified as OPN-coated degenerated neurites. This study investigates the spatiotemporal relationship between punctate OPN deposition and astroglial and microglial reactions elicited by 3-nitropropionic acid (3-NP).MethodsMale Sprague-Dawley rats were intraperitoneally… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 79 REFERENCES

Similar Papers

Loading similar papers…