Osteopontin: a new emerging role in psoriasis

Abstract

Osteopontin (OPN) is a phosphorylated acidic glycoprotein produced by cells of the immune system, epithelial tissue, smooth muscle cells, osteoblasts, and tumor cells. OPN interacts with integrins and CD44 to enhance Th1 and inhibit Th2 cytokine expression. The involvement of this molecule in the onset of psoriasis has not previously been studied. Here, we… (More)
DOI: 10.1007/s00403-009-0939-5

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Cite this paper

@article{Buommino2009OsteopontinAN, title={Osteopontin: a new emerging role in psoriasis}, author={Elisabetta Buommino and Maria Antonietta Tufano and Anna Balato and Nunzia Canozo and Maria Donnarumma and Lucia Gallo and Fabio Ayala}, journal={Archives of Dermatological Research}, year={2009}, volume={301}, pages={397-404} }