Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification.

@article{Cho2009OsteopontinAM,
  title={Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification.},
  author={Hyun-ju Cho and H Cho and Hyo Soo Kim},
  journal={Current atherosclerosis reports},
  year={2009},
  volume={11 3},
  pages={206-13}
}
Osteopontin (OPN) was initially identified in osteoblasts as a mineralization-modulatory matrix protein. Recently, OPN has been studied as a multifunctional protein that is upregulated in a variety of acute and chronic inflammatory conditions, such as wound healing, fibrosis, autoimmune disease, and atherosclerosis. OPN is highly expressed at sites with… CONTINUE READING