Osteopontin: Versatile modulator of liver diseases.

  • Sumiko Nagoshi
  • Published 2014 in
    Hepatology research : the official journal of the…


Osteopontin (OPN) is a multifunctional protein, involved in pathological conditions including inflammation, immunity, angiogenesis, fibrosis and cancer progression in various tissues. Hepatic inflammation and fibrosis induced by feeding with a diet deficient in methionine and choline (MCD diet) were markedly attenuated in OPN knockout mice when compared… (More)
DOI: 10.1111/hepr.12166


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