Osteopontin, a substrate for transglutaminase and factor XIII activity.

@article{Prince1991OsteopontinAS,
  title={Osteopontin, a substrate for transglutaminase and factor XIII activity.},
  author={Charles W. Prince and Dr Andrew S. Dickie and Carlos L Krumdieck},
  journal={Biochemical and biophysical research communications},
  year={1991},
  volume={177 3},
  pages={1205-10}
}
Osteopontin (OPN), an extracellular matrix cell adhesion protein, was found to serve as a substrate for the incorporation of radiolabelled putrescine mediated by a commercial preparation of guinea pig liver transglutaminase. Preliminary evidence also suggests that OPN serves as a substrate for the plasma transglutaminase, Factor XIIIa. While the protein substrates to which OPN is linked in vivo have not been identified, it is reasonable to speculate that this capacity of OPN may dictate its… CONTINUE READING