Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment.

@article{Ficarra2005OsteonecrosisOT,
  title={Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment.},
  author={Giuseppe Ficarra and Francesco Beninati and Ida Rubino and Alessandro Vannucchi and Giuseppe Longo and Pietro Tonelli and Giovan Paolo Pini Prato},
  journal={Journal of clinical periodontology},
  year={2005},
  volume={32 11},
  pages={
          1123-8
        }
}
BACKGROUND/AIM Osteonecrosis of the jaws is being increasingly reported in patients with bone metastasis from a variety of solid tumours and disseminated multiple myeloma receiving intra-venous bisphosphonates. The signs and symptoms that may occur before the appearance of clinical evident osteonecrosis include changes in the health of periodontal tissues, non-healing mucosal ulcers, loose teeth and unexplained soft-tissue infection. A series of nine periodontally involving patients showing… CONTINUE READING
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