Osteonecrosis of the external auditory canal associated with oral bisphosphonate therapy: case report and literature review.

@article{Salzman2013OsteonecrosisOT,
  title={Osteonecrosis of the external auditory canal associated with oral bisphosphonate therapy: case report and literature review.},
  author={Richard Salzman and Jir{\'i} Hoza and Vojtěch Peřina and Ivo St{\'a}rek},
  journal={Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology},
  year={2013},
  volume={34 2},
  pages={209-13}
}
OBJECTIVE To present the first case of a patient with oral bisphosphonates-associated ear canal osteonecrosis (BPECO), review previously published cases, and suggest a definition of BPECO. PATIENT A 79-year-old woman with left otorrhea and earache was treated for otitis externa for 2 months. The examination revealed a deep floor of the left ear canal defect. The bisphosphonates were discontinued. By the end of the 6-week-course of intravenous antibiotics, the bone defect progression ceased… CONTINUE READING
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