Osteointegration in cranial bone reconstruction: a goal to achieve.

  title={Osteointegration in cranial bone reconstruction: a goal to achieve.},
  author={Simone Sprio and Marco Fricia and Giuseppe F Maddalena and Angelo Nataloni and Anna Tampieri},
  journal={Journal of applied biomaterials & functional materials},
  volume={14 4},
BACKGROUND The number of cranioplasty procedures is steadily increasing, mainly due to growing indications for decompressive procedures following trauma, tumor or malformations. Although autologous bone is still considered the gold standard for bone replacement in skull, there is an urgent need for synthetic porous implants able to guide bone regeneration and stable reconstruction of the defect. In this respect, hydroxyapatite scaffolds with highly porous architecture are very promising… CONTINUE READING