Osteoimmunology and osteoporosis

@inproceedings{Geusens2011OsteoimmunologyAO,
  title={Osteoimmunology and osteoporosis},
  author={Piet P. Geusens and Willem Frederik Lems},
  booktitle={Arthritis research & therapy},
  year={2011}
}
The concept of osteoimmunology is based on growing insight into the links between the immune system and bone at the anatomical, vascular, cellular, and molecular levels. In both rheumatoid arthritis (RA) and ankylosing spondylitis (AS), bone is a target of inflammation. Activated immune cells at sites of inflammation produce a wide spectrum of cytokines in favor of increased bone resorption in RA and AS, resulting in bone erosions, osteitis, and peri-inflammatory and systemic bone loss. Peri… CONTINUE READING
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