Osteogenicity of biphasic calcium phosphate ceramics and bone autograft in a goat model.

@article{Fellah2008OsteogenicityOB,
  title={Osteogenicity of biphasic calcium phosphate ceramics and bone autograft in a goat model.},
  author={Borhane Hakim Fellah and Olivier Gauthier and Pierre Weiss and Daniel Chappard and Pierre Layrolle},
  journal={Biomaterials},
  year={2008},
  volume={29 9},
  pages={
          1177-88
        }
}
The aim of this work was to compare the osteogenicity of calcium phosphate ceramic granules with autologous bone graft in ectopic and orthotopic sites. Biphasic calcium phosphate (BCP) granules composed of hydroxyapatite (HA) and beta-tricalcium phosphate (beta-TCP) in a 60/40 ratio were sintered at 1050, 1125 and 1200 degrees C, producing different microporosities. Either BCP ceramic granules or autologous bone chips (n=7) were implanted into paraspinal muscles. Osteoinduction was not observed… CONTINUE READING
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