Osteogenic potential for replacing cells in rat cranial defects implanted with a DNA/protamine complex paste.


Osteoinductive scaffolds are required for bone tissue engineering. The aim of the present study was to assess the osteoinductive capacity of deoxyribonucleic acid (DNA)/protamine complexes in a rat model of critical-size calvarial defects. In addition, we investigated whether cultured mesenchymal-like cells (DP-cells) outgrown from DNA/protamine complex… (More)
DOI: 10.1016/j.bone.2014.07.018


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