Osteogenic medium is superior to growth factors in differentiation of human adipose stem cells towards bone-forming cells in 3D culture.

@article{Tirkkonen2013OsteogenicMI,
  title={Osteogenic medium is superior to growth factors in differentiation of human adipose stem cells towards bone-forming cells in 3D culture.},
  author={Laura Tirkkonen and Suvi P. Haimi and Satu Huttunen and Johannes Ernst Alexander Wolff and Eija Pirhonen and George K. B. S{\'a}ndor and Susanna Miettinen},
  journal={European cells & materials},
  year={2013},
  volume={25},
  pages={144-58}
}
Human adipose stem cells (hASCs) have been recently used to treat bone defects in clinical practice. Yet there is a need for more optimal scaffolds and cost-effective approaches to induce osteogenic differentiation of hASCs. Therefore, we compared the efficiency of bone morphogenetic proteins (BMP-2 and BMP-7), vascular endothelial growth factor (VEGF), and osteogenic medium (OM) for the osteo-induction of hASCs in 3D culture. In addition, growth factors were tested in combination with OM… CONTINUE READING
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