Osteogenic markers are reduced in bone-marrow mesenchymal cells and femoral bone of young spontaneously hypertensive rats.

@article{Barros2016OsteogenicMA,
  title={Osteogenic markers are reduced in bone-marrow mesenchymal cells and femoral bone of young spontaneously hypertensive rats.},
  author={Thamine Landim de Barros and Victor Gustavo Balera Brito and Caril Constante Ferreira do Amaral and Ant{\^o}nio Hernandes Chaves-Neto and Ana Paula Campanelli and Sandra Helena Penha de Oliveira},
  journal={Life sciences},
  year={2016},
  volume={146},
  pages={174-83}
}
AIMS Spontaneously hypertensive rats (SHR) and normotensive rats (W) has significant changes in bone metabolism. The purpose of this study was to investigate whether, the genetic predisposition, is sufficient to induce changes in the osteoblast differentiation and osteogenic markers in the BMSCs or in the femoral bone. For this we use young SHR rats without hypertension, but, with genetic predisposition in compared with young W. MAIN METHODS BMSCs were cultured in a proliferation medium (MEM… CONTINUE READING