Osteogenic growth peptide promotes osteogenic differentiation of mesenchymal stem cells mediated by LncRNA AK141205-induced upregulation of CXCL13.

@article{Li2015OsteogenicGP,
  title={Osteogenic growth peptide promotes osteogenic differentiation of mesenchymal stem cells mediated by LncRNA AK141205-induced upregulation of CXCL13.},
  author={H. Li and Zhonghe Zhang and Z. Chen and D. Zhang},
  journal={Biochemical and biophysical research communications},
  year={2015},
  volume={466 1},
  pages={
          82-8
        }
}
  • H. Li, Zhonghe Zhang, +1 author D. Zhang
  • Published 2015
  • Biology, Medicine
  • Biochemical and biophysical research communications
  • The aim of present study was to characterize long non-coding RNA (lncRNA) AK141205 as a cellular regulator of osteogenic differentiation of mice mesenchymal stem cells (MSCs) towards osteogenic growth peptide (OGP) stimulation. Mice MSCs cells were isolated, transfected with si-AK141205, pcDNA-AK141205 or control, and stimulated with OGP. The AK141205, CXC chemokine ligand-13 (CXCL13), and osteogenic differentiation-associated parameters were determined by western blotting or quantitative RT… CONTINUE READING
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