Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling.

@article{Wan2006OsteogenicDO,
  title={Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling.},
  author={Derrick C Wan and Yun-ying Shi and Randall P Nacamuli and Natalina Quarto and Karen M Lyons and Michael Thornton Longaker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 33},
  pages={12335-40}
}
Although the multilineage potential of human adipose-derived adult stromal cells (ADAS) has been well described, few published studies have investigated the biological and molecular mechanisms underlying osteogenic differentiation of mouse ADAS. We report here that significant osteogenesis, as determined by gene expression and histological analysis, is… CONTINUE READING