Osteogenic differentiation of human mesenchymal stem cells synergistically enhanced by biomimetic peptide amphiphiles combined with conditioned medium.

@article{Anderson2011OsteogenicDO,
  title={Osteogenic differentiation of human mesenchymal stem cells synergistically enhanced by biomimetic peptide amphiphiles combined with conditioned medium.},
  author={Joel Matthew Anderson and Jeremy B. Vines and Jessica L Patterson and Haiyan Chen and Amjad Javed and Ho-wook Jun},
  journal={Acta biomaterialia},
  year={2011},
  volume={7 2},
  pages={
          675-82
        }
}
An attractive strategy for bone tissue engineering is the use of extracellular matrix (ECM) analogous biomaterials capable of governing biological response based on synthetic cell-ECM interactions. In this study, peptide amphiphiles (PAs) were investigated as an ECM-mimicking biomaterial to provide an instructive microenvironment for human mesenchymal stem cells (hMSCs) in an effort to guide osteogenic differentiation. PAs were biologically functionalized with ECM isolated ligand sequences (i.e… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 64 REFERENCES

Similar Papers

Loading similar papers…