Osteogenesis imperfecta and hearing loss.

  title={Osteogenesis imperfecta and hearing loss.},
  author={Margriet Verstreken and Jos Claes and Paul Van de Heyning},
  journal={Acta oto-rhino-laryngologica Belgica},
  volume={50 2},
A review of the literature of osteogenesis imperfecta (OI) and hearing loss in the last century is given. This includes the first association in 1912 by Adair-Dighton of OI with hearing loss, the triad of VAN DER HOEVE and DE KLEYN and different clinical and audiometric studies and classifications of the disease. A case report of a 14 year old patient is also included. The genetics of OI and the complexity in correlating genetics with clinical classifications is elucidated. Finally, the… CONTINUE READING