Osteogenesis imperfecta--clinical and molecular diversity.


Osteogenesis imperfecta is a heritable disorder of bone formation resulting in low bone mass and a propensity to fracture. It exhibits a broad range of clinical severity, ranging from multiple fracturing in utero and perinatal death to normal adult stature and a low fracture incidence. The disorder is currently classified into seven types based on… (More)


2 Figures and Tables

Cite this paper

@article{Roughley2003OsteogenesisIA, title={Osteogenesis imperfecta--clinical and molecular diversity.}, author={Peter J. Roughley and Frank Rauch and Fr{\'e}d{\'e}ric Glorieux}, journal={European cells & materials}, year={2003}, volume={5}, pages={41-7; discussion 47} }