Osteogenesis imperfecta--clinical and molecular diversity.

Abstract

Osteogenesis imperfecta is a heritable disorder of bone formation resulting in low bone mass and a propensity to fracture. It exhibits a broad range of clinical severity, ranging from multiple fracturing in utero and perinatal death to normal adult stature and a low fracture incidence. The disorder is currently classified into seven types based on… (More)

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Cite this paper

@article{Roughley2003OsteogenesisIA, title={Osteogenesis imperfecta--clinical and molecular diversity.}, author={Peter J. Roughley and Frank Rauch and Fr{\'e}d{\'e}ric Glorieux}, journal={European cells & materials}, year={2003}, volume={5}, pages={41-7; discussion 47} }