Osteocyte regulation of the function of the executive cells of bone remodeling : the Sost / sclerostin paradigm

@inproceedings{Bellido2006OsteocyteRO,
  title={Osteocyte regulation of the function of the executive cells of bone remodeling : the Sost / sclerostin paradigm},
  author={Teresita M. Bellido},
  year={2006}
}
It has been long postulated that osteocytes initiate the adaptive response of bone to mechanical stimuli. Osteoblasts and osteoclasts are present on bone only transiently, in low number, and in variable locations. Osteocytes, on the other hand, are the most abundant resident cells (compared to lining and periosteal cells) and are present in the entire bone… CONTINUE READING