Osteocyte-based image analysis for quantitation of histologically apparent femoral head osteonecrosis: application to an emu model.

@article{Reed2004OsteocytebasedIA,
  title={Osteocyte-based image analysis for quantitation of histologically apparent femoral head osteonecrosis: application to an emu model.},
  author={Karen L Reed and Michael G. Conzemius and Robert A Robinson and Thomas D. Brown},
  journal={Computer methods in biomechanics and biomedical engineering},
  year={2004},
  volume={7 1},
  pages={25-32}
}
Femoral head osteonecrosis is often characterized histologically by the presence of empty lacunae in the affected bony regions. The shape, size and location of a necrotic lesion influences prognosis, and can, in principle, be quantified by mapping the distribution of empty lacunae within a femoral head. An algorithm is here described that automatically identifies the locations of osteocyte-filled vs. empty lacunae. The algorithm is applied to necrotic lesions surgically induced in the emu, a… CONTINUE READING

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