Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.

@article{Takei2016OsteoclastogenicDO,
  title={Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.},
  author={Yuichiro Takei and Teruyoshi Tanaka and K. Craig Kent and Dai Yamanouchi},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2016},
  volume={36 9},
  pages={1962-71}
}
OBJECTIVE Arterial calcification is common and contributes to the pathogenesis of occlusive vascular disease. Similar to the dynamics of bone, it is a tightly controlled process that maintains a balance between osteogenesis and osteolysis. However, whether calcium homeostasis plays a role in the development of aneurysms has not been explored. We hypothesized that macrophages differentiate into osteoclasts in aneurysmal arteries and that protease byproducts contribute to aneurysm pathophysiology… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-4 of 4 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Inverse Correlation Between Calcium Accumulation and the Expansion Rate of Abdominal Aortic Aneurysms.

Circulation journal : official journal of the Japanese Circulation Society • 2016

Aneurysmal disease: the abdominal aorta.

The Surgical clinics of North America • 2013
View 2 Excerpts

Calcification as a risk factor for rupture of abdominal aortic aneurysm.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery • 2013

Current status of medical treatment for abdominal aortic aneurysm.

Circulation journal : official journal of the Japanese Circulation Society • 2013
View 3 Excerpts

Similar Papers

Loading similar papers…