Osteoclast recruitment to sites of compression in orthodontic tooth movement.

  title={Osteoclast recruitment to sites of compression in orthodontic tooth movement.},
  author={W J Rody and Gregory Joseph King and Guozhong Gu},
  journal={American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics},
  volume={120 5},
Although it is widely acknowledged that osteoclasts are formed by the fusion of mononuclear cells of hematopoietic origin, it has been extremely difficult to understand how they originate after appliance activation. The purpose of this study was to quantify osteoclast recruitment at compression sites as a function of time following orthodontic force application. Appliances were placed in 96 rats. At day 0, the animals were randomized to either appliance activation or sham activation followed by… CONTINUE READING
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