Osteoclast formation in bone marrow cultures from two inbred strains of mice with different bone densities.

@article{Linkhart1999OsteoclastFI,
  title={Osteoclast formation in bone marrow cultures from two inbred strains of mice with different bone densities.},
  author={Thomas A. Linkhart and S G Linkhart and Yuzo Kodama and John R. Farley and Hans Peter Dimai and Kenneth R. Wright and Jon E. Wergedal and Matilda H. C. Sheng and Wesley G. Beamer and Leah Rae B Donahue and Clifford J. Rosen and David J. Baylink},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1999},
  volume={14 1},
  pages={39-46}
}
For the purpose of identifying genes that affect bone volume, we previously identified two inbred mouse strains (C57BL/6J and C3H/HeJ) with large differences in femoral bone density and medullary cavity volume. The lower density and larger medullary cavity volume in C57BL/6J mice could result from either decreased formation or increased resorption or both. We recently reported evidence suggesting that bone formation was increased in vivo and that osteoblast progenitor cells are more numerous in… CONTINUE READING
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