Osteocalcin and matrix GLA protein in developing teleost teeth: identification of sites of mRNA and protein accumulation at single cell resolution

@article{OrtizDelgado2005OsteocalcinAM,
  title={Osteocalcin and matrix GLA protein in developing teleost teeth: identification of sites of mRNA and protein accumulation at single cell resolution},
  author={Juan Bosco Ortiz-Delgado and Dina C. Simes and Paulo J. Gavaia and Carmen Sarasquete and Maria Leonor Cancela},
  journal={Histochemistry and Cell Biology},
  year={2005},
  volume={124},
  pages={123-130}
}
In this study, the tissue distribution and accumulation of osteocalcin or bone Gla protein (BGP) and matrix Gla protein (MGP) were determined during tooth development in a teleost fish, Argyrosomus regius. In this species, the presence of BGP and MGP mRNA in teeth was revealed by in situ hybridization. mRNA for BGP was detected in the odontoblasts as well as in its cytoplasmic processes emerging through dentinal tubules, while mRNA for MGP was expressed in the enamel portion within the apical… CONTINUE READING

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