Osteocalcin and its message: relationship to bone histology in magnesium-deprived rats.

@article{Carpenter1992OsteocalcinAI,
  title={Osteocalcin and its message: relationship to bone histology in magnesium-deprived rats.},
  author={Thomas O. Carpenter and Slawomir Mackowiak and Nancy W Troiano and Caren M. Gundberg},
  journal={The American journal of physiology},
  year={1992},
  volume={263 1 Pt 1},
  pages={E107-14}
}
These studies examine effects of brief Mg deprivation on bone histomorphometry and on secretion and synthesis of the specific osteoblast product, osteocalcin. Osteocalcin mRNA was determined in calvaria-derived cells and was correlated to circulating concentrations of the protein after 8 days of Mg deprivation. Circulating osteocalcin was decreased in Mg-deprived rats when compared with pair-fed normal rats after 8 days of Mg deprivation, with no significant changes in calcium or 1,25… CONTINUE READING

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