Osteoblasts generate harder, stiffer, and more delamination-resistant mineralized tissue on titanium than on polystyrene, associated with distinct tissue micro- and ultrastructure.

@article{Saruwatari2005OsteoblastsGH,
  title={Osteoblasts generate harder, stiffer, and more delamination-resistant mineralized tissue on titanium than on polystyrene, associated with distinct tissue micro- and ultrastructure.},
  author={Lei Saruwatari and Hideki Aita and Frank Butz and Hiromi Nakamura and Jianyong Ouyang and Yang Yang and Wen-An Chiou and Takahiro Ogawa},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2005},
  volume={20 11},
  pages={2002-16}
}
UNLABELLED This study revealed that osteoblasts generate harder, stiffer, and more delamination-resistant mineralized tissue on titanium than on the tissue culture polystyrene, associated with modulated gene expression, uniform mineralization, well-crystallized interfacial calcium-phosphate layer, and intensive collagen deposition. Knowledge of this titanium-induced alteration of osteogenic potential leading to enhanced intrinsic biomechanical properties of mineralized tissue provides novel… CONTINUE READING
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