Osteoblast-like cell adhesion to bone sialoprotein peptides.

@article{Rapuano2004OsteoblastlikeCA,
  title={Osteoblast-like cell adhesion to bone sialoprotein peptides.},
  author={Bruce E. Rapuano and Ching-Tang Wu and Daniel Macdonald},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2004},
  volume={22 2},
  pages={
          353-61
        }
}
A number of studies have suggested that biomimetic peptides can be used in the design of a new generation of prosthetic implants to promote the successful biointegration of the implant materials. In the current study, the in vitro bioactivities of several peptides representing RGD (Arg-Gly-Asp)-containing sequences of bone sialoprotein (BSP) toward an osteoblast-like cell line (MC3T3-E1) were examined to provide insight into the molecular basis of BSP's interaction with bone cells. BSP residues… CONTINUE READING
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