Osteoblast behaviour on HA/PE composite surfaces with different HA volumes.

  title={Osteoblast behaviour on HA/PE composite surfaces with different HA volumes.},
  author={Lucy Di Silvio and Matthew J. Dalby and William Bonfield},
  volume={23 1},
A hydroxyapatite (HA) reinforced polyethylene (PE) composite (designated HAPEX), with high mechanical specification and a bioactive HA phase, has been optimised as a bone analogue material. Manufacturing conditions and machining of the materials were carefully controlled to give a reproducible material surface roughness with minimal batch variation. The effect of surface composition was examined in vitro using primary human osteoblasts (HOB). HOBs were cultured in direct contact with the test… CONTINUE READING

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