Osteoarthritis, inflammation and obesity.

  title={Osteoarthritis, inflammation and obesity.},
  author={Francis Berenbaum and Florent Eymard and Xavier Houard},
  journal={Current opinion in rheumatology},
  volume={25 1},
PURPOSE OF REVIEW Obesity is one of the main risk factors of the incidence and prevalence of knee osteoarthritis. Recent epidemiological data showing an increased risk of hand osteoarthritis in obese patients opened the door to a role of systemic inflammatory mediators, adipokines, released by adipose tissue. RECENT FINDINGS Recent experimental studies confirm the critical roles of adipokines in the pathophysiologic features of osteoarthritis, with an emphasis on a new member, chemerin… CONTINUE READING