Osteo-/odontogenic differentiation of induced mesenchymal stem cells generated through epithelial-mesenchyme transition of cultured human keratinocytes.

@article{Yi2014OsteoodontogenicDO,
  title={Osteo-/odontogenic differentiation of induced mesenchymal stem cells generated through epithelial-mesenchyme transition of cultured human keratinocytes.},
  author={Jin-Kyu Yi and Shebli Mehrazarin and J Oh and Anu Bhalla and Jenessa Oo and Wei Chen and Min Lee and R H Kim and K H Shin and N H Park and Mo K Kang},
  journal={Journal of endodontics},
  year={2014},
  volume={40 11},
  pages={1796-801}
}
INTRODUCTION Revascularization of necrotic pulp has been successful in the resolution of periradicular inflammation; yet, several case studies suggest the need for cell-based therapies using mesenchymal stem cells (MSCs) as an alternative for de novo pulp regeneration. Because the availability of MSCs may be limited, especially in an aged population, the current study reports an alternative approach in generating MSCs from epidermal keratinocytes through a process called epithelial-mesenchymal… CONTINUE READING

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