Osteitis and synovitis, but not bone erosion, is associated with proteoglycan loss and microstructure damage in the cartilage of patients with rheumatoid arthritis.

@article{Herz2014OsteitisAS,
  title={Osteitis and synovitis, but not bone erosion, is associated with proteoglycan loss and microstructure damage in the cartilage of patients with rheumatoid arthritis.},
  author={Barbara Herz and Andreas Albrecht and Matthias Englbrecht and G{\"o}tz Hannes Welsch and Michael Uder and Nina Renner and Philipp Martin Schlechtweg and Dominik Paul and Lars Lauer and Klaus Engelke and Rolf Janka and J{\"u}rgen Rech and Georg Schett and Stephanie Finzel},
  journal={Annals of the rheumatic diseases},
  year={2014},
  volume={73 6},
  pages={1101-6}
}
OBJECTIVES To investigate the relation between anatomic changes of the synovium, the bone, the bone marrow and the cartilage to biochemical properties of the cartilage in patients with rheumatoid arthritis (RA). METHODS 33 patients with RA received 3-T MRI scans of the metacarpophalangeal joints. Two independent methods, (A) the delayed gadolinium enhanced MRI of the cartilage (dGEMRIC, T2-mapping), which was used to assess the biochemical properties of the cartilage; (B) synovitis, osteitis… CONTINUE READING

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