Osseous metaplasia within a urothelial bladder cancer nodal metastasis: a case report.

Abstract

BACKGROUND Osseous metaplasia within bladder cancer is extremely rare and, to our knowledge, has not been previously reported within a urothelial bladder carcinoma (UBC) nodal metastasis. CASE A 78-year-old man underwent radical cystoprostatectomy because of high-grade pT2 UBC. Pathology revealed a high-grade pT4aN2 UBC with osseous metaplasia into a massively metastatic lymph node but not into the primary bladder tumor. CONCLUSION Based independently on its location, this finding warrants a careful differential diagnosis with sarcomatoid bladder tumors and is likely to be a marker of tumor aggressiveness, thus recommending aggressive treatment.

Cite this paper

@article{Cormio2014OsseousMW, title={Osseous metaplasia within a urothelial bladder cancer nodal metastasis: a case report.}, author={Luigi Cormio and Francesca Sanguedolce and Paolo Massenio and Giuseppe Di Fino and Oscar Selvaggio and Pantaleo Bufo and Giuseppe Carrieri}, journal={Analytical and quantitative cytopathology and histopathology}, year={2014}, volume={36 2}, pages={117-9} }