Osseous Hodgkin disease.

@article{Ostrowski1999OsseousHD,
  title={Osseous Hodgkin disease.},
  author={Mary L. Ostrowski and Carrie Y. Inwards and John G. Strickler and Thomas E Witzig and Doris E. Wenger and Krishnan K. Unni},
  journal={Cancer},
  year={1999},
  volume={85 5},
  pages={1166-78}
}
BACKGROUND Hodgkin disease rarely presents as an osseous lesion, and the majority of patients are found at staging to have concurrent disease in lymph nodes. Many cases of osseous Hodgkin disease have been misdiagnosed on initial biopsy. METHODS All cases of Hodgkin disease diagnosed by open bone biopsy at the Mayo Clinic were identified. These included patients with primary osseous tumors, those presenting with multiple sites of involvement (with osseous lesions), and those with recurrence… CONTINUE READING

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Three patients had solitary , osseous tumors and two had primary , multifocal , osseous Hodgkin disease without involvement of nonosseous sites .
Patients with concurrent osseous and nonosseous tumors exhibited a 60% overall survival rate , but at last follow - up all 4 patients diagnosed after 1986 still were alive ; those with Hodgkin disease that recurred as osseous lesions had a 60% survival rate at 8 years , but only 1 of the 5 patients diagnosed since 1984 had died of disease .
Twelve patients who presented with lesions in osseous sites also had nonosseous tumors detected at staging , and 8 patients had recurrent Hodgkin disease that presented in bone .
Three patients had solitary , osseous tumors and two had primary , multifocal , osseous Hodgkin disease without involvement of nonosseous sites .
Twelve patients who presented with lesions in osseous sites also had nonosseous tumors detected at staging , and 8 patients had recurrent Hodgkin disease that presented in bone .
Patients with concurrent osseous and nonosseous tumors exhibited a 60% overall survival rate , but at last follow - up all 4 patients diagnosed after 1986 still were alive ; those with Hodgkin disease that recurred as osseous lesions had a 60% survival rate at 8 years , but only 1 of the 5 patients diagnosed since 1984 had died of disease .
Three patients had solitary , osseous tumors and two had primary , multifocal , osseous Hodgkin disease without involvement of nonosseous sites .
Three patients had solitary , osseous tumors and two had primary , multifocal , osseous Hodgkin disease without involvement of nonosseous sites .
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