Osseointegration of hydroxyapatite-coated and noncoated Ti6Al4V implants in the presence of local infection: a comparative histomorphometrical study in rabbits.

@article{Oosterbos2002OsseointegrationOH,
  title={Osseointegration of hydroxyapatite-coated and noncoated Ti6Al4V implants in the presence of local infection: a comparative histomorphometrical study in rabbits.},
  author={Cornelis Kees J M Oosterbos and Henri C Vogely and Marc W. Nijhof and Andr{\'e} Fleer and Abraham J. Verbout and Alphons J Tonino and Wouter J. A. Dhert},
  journal={Journal of biomedical materials research},
  year={2002},
  volume={60 3},
  pages={339-47}
}
A study was designed to investigate the osseointegration of titanium implants, either noncoated or coated with hydroxyapatite (HA), into rabbit tibiae in the presence of local infection compared with osseointegration in the absence of local infection. HA-coated or noncoated Ti cylinders were implanted into both tibiae of 32 rabbits (New Zealand Whites). Before implantation the left tibia was contaminated with different quantities of Staphylococcus aureus (10(2)-10(5) CFU). Four weeks after… CONTINUE READING

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