Osseointegration: the slow delivery of BMP-2 enhances osteoinductivity.

@article{Hunziker2012OsseointegrationTS,
  title={Osseointegration: the slow delivery of BMP-2 enhances osteoinductivity.},
  author={Ernst Bruno Hunziker and Lukas Enggist and Alexander F K{\"u}ffer and Daniel Ch. Buser and Yu Liu},
  journal={Bone},
  year={2012},
  volume={51 1},
  pages={98-106}
}
Although the placement of dental and orthopedic implants is now generally a safe, reliable and successful undertaking, the functional outcome is less assured in patients whose bone-healing capacity is compromised. To enhance peri-implant osteogenesis in these individuals, BMP-2 could be locally administered. However, neither a free suspension nor an implant-adsorbed depot of the agent is capable of triggering sustained bone formation. We hypothesize that this end could be achieved by… CONTINUE READING

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